The most notable inclusion in the Italy squad is Torino forward Andrea Belotti, who netted 15 times this season, although Serie A top scorer Fabio Quagliarella is likely to start up front.
Goalkeeper Gianluigi Donnarumma is out injured so there is a call up for Atalanta stopper Pierluigi Gollini.
Greece lost 2-1 in a friendly against Turkey last weekend, but were without first choice centre-back pairing Kostas Manolas and Sokratis Papastathopoulos, who will both return this Saturday.
The natural angle for this game is to oppose goals, with these two sides both being relatively strong in defence while lacking a cutting edge up front.
Under 2.5 goals has paid out in eight of Italy’s last nine matches in all competitions while proving the correct selection in 10 of the last 13 matches Greece have contested.
It is understandable therefore to see a repeat offered at 23/50 (1.46) and Saturday’s game seems almost certain to be a tight affair.
Italy have kept four consecutive clean sheets, while Greece have failed to score in three of their last five home matches and perhaps there should be some interest in opposing the hosts to get on the scoresheet.
Tips and predictions
Angelos Anastasiadis’ are priced at 27/25 (2.08) to score under 0.5 goals and finding the back of the net has long since been a problem for Greece.
Against an Italian side yet to concede in qualifying, the Hellenic nation could struggle once more in the final third. Backing Italy to win to nil could also be an option at 37/20 (2.85).